Dra. Cecilia Besa C.

Radiología

Cargo


Profesor Asistente

Teléfono


(+56)2 23548243

Contacto


cbesa@med.puc.cl

Formación Pregrado:

Médico Cirujano, Universidad de los Andes.

Formación Postgrado:

  • Médico Radiólogo, Pontificia Universidad Católica de Chile.
  • Fellowship clínico en Imágenes Oncológicas e Imágenes abdominales, Icahn School of Medicine at Mount Sinai Medical School, New York, USA,  2012-2015.
  • Fellowship en Clinical PET/CT, Washington University in Saint Louis, USA, 2011-2012.

Líneas de investigación:

Imágenes por Resonancia Magnética, Radiología quantitativa, Biomarcadores de imágenes no invasivos, Enfermedad hepática focal y difusa.

Publicaciones:

  1. Gordic S, Wagner M, Zanato R, Hectors S, Besa C, Kihira S, Kim E, Taouli B. Prediction of hepatocellular carcinoma response to 90Yttrium radioembolization using volumetric ADC histogram quantification: preliminary results. Cancer Imaging. 2019 May 29;19(1):29. PMID: 31142363
  2. Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O’Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Kinahan PE, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X. The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge, Part II. 2019 Mar;5(1):99-109. PMID: 30854447
  3. Hectors SJ, Wagner M, Besa C, Huang W, Taouli B. Multiparametric FDG-PET/MRI of Hepatocellular Carcinoma: Initial Experience. Contrast Media Mol Imaging. 2018 Oct 3; 2018:5638283. PMID 30402045
  4. Wagner M, Hectors S, Bane O, Gordic S, Kennedy P, Besa C, Schiano TD, Thung S, Fischman A, Taouli B. Noninvasive prediction of portal pressure with MR elastography and DCE-MRI of the liver and spleen: Preliminary results. J Magn Reson Imaging. 2018 Oct;48(4):1091-1103. PMID: 29638020
  5. Arenas A, Urzúa Á, Poniachik J, Carlos Diaz J, Castillo J, Saure A, Lembach H, Cancino A, Ibarra J, Besa C, Wolff R, Arrese M, Benítez C. Reversibility of Acquired Hepatocerebral Degeneration After Liver Transplantation. Liver Transpl. 2018 Aug;24(8):1133-1137. PMID: 30142251
  6. Besa C, Wagner M, Lo G, Gordic S, Chatterji M, Kennedy P, Stueck A, Thung S, Babb J, Smith A, Taouli B. Detection of liver fibrosis using qualitative and quantitative MR elastography compared to liver surface nodularity measurement, gadoxetic acid uptake, and serum markers. J Magn Reson Imaging. 2018 Jun;47(6):1552-1561. PMID: 29193508
  7. Lewis S, Besa C, Wagner M, Jhaveri K, Kihira S, Zhu H, Sadoughi N, Fischer S, Srivastava A, Yee E, Mortele K, Babb J, Thung S, Taouli B. Prediction of the histopathologic findings of intrahepatic cholangiocarcinoma: qualitative and quantitative assessment of diffusion-weighted imaging. Eur Radiol. 2018 May;28(5):2047-2057. PMID 29234913
  8. Wagner M, Ko HM, Chatterji M, Besa C, Torres J, Zhang X, Panchal H, Hectors S, Cho J, Colombel JF, Harpaz N, Taouli B. Magnetic Resonance Imaging Predicts Histopathological Composition of Ileal Crohn’s Disease. J Crohns Colitis. 2018 May 25;12(6):718-729. PMID:29300851
  9. Gordic S, Corcuera-Solano I, Stueck A, Besa C, Argiriadi P, Guniganti P, King M, Kihira S, Babb J, Thung S, Taouli B. Evaluation of HCC response to locoregional therapy: Validation of MRI-based response criteria versus explant pathology. J Hepatol. 2017 Dec;67(6):1213-1221. PMID 28823713
  10. Hectors SJ, Wagner M, Bane O, Besa C, Lewis S, Remark R, Chen N, Fiel MI, Zhu H, Gnjatic S, Merad M, Hoshida Y, Taouli B. Quantification of hepatocellular carcinoma heterogeneity with multiparametric magnetic resonance imaging. Sci Rep. 2017 May 26;7(1):2452. PMID: 28550313
  11. Goossens N, Singal AG, King LY, Andersson KL, Fuchs BC, Besa C, Taouli B, Chung RT, Hoshida Y. Cost Effectiveness of Risk Score-Stratified Hepatocellular Carcinoma Screening in Patients with Cirrhosis. Clin Transl Gastroenterol. 2017 Jun 22;8(6):e101. PMID: 28640287
  12. Swinburne NC, Biederman DM, Besa C, Tabori NE, Fischman AM, Patel RS, Nowakowski FS, Gunasekaran G, Schwartz ME, Lookstein RA, Kim E. Radioembolization for Unresectable Intrahepatic Cholangiocarcinoma:Review of Safety, Response Evaluation Criteria in Solid Tumors 1.1 Imaging Response and Survival. Cancer Biother Radiopharm. 2017 Jun;32(5):161-168. PMID: 28598685
  13. Lo GC, Besa C, King MJ, Kang M, Stueck A, Thung S, Wagner M, Smith AD, Taouli B. Feasibility and reproducibility of liver surface nodularity quantification for the assessment of liver cirrhosis using CT and MRI. Eur J Radiol Open. 2017 Jul 21;4:95100. PMID:28761907
  14. Sagalovich D, Besa C, Tran TY, Thummar H, Le Grand B, Taouli B, Gupta M. Prone Percutaneous Nephrolithotomy: Does Bolster Orientation Matter? Urology. 2017 Jul 18. pii: S0090- 4295(17)30730-6. PMID: 28733201
  15. Lewis S, Besa C,Rosen A, Rastinehad AR, Semaan S, Hectors S, Taouli B. Multiparametric magnetic resonance imaging for transition zone prostate cancer: essential findings, limitations, and future directions. Abdom Radiol (NY). 2017 Jul 12. PMID: 28702787
  16. Gordic S, Ayache JB, Kennedy P, Besa C, Wagner M, Bane O, Ehman RL, Kim E, Taouli B. Value of tumor stiffness measured with MR elastography for assessment of response of hepatocellular carcinoma to locoregional therapy. Abdom Radiol (NY). 2017 Feb 2. PMID: 28154910
  17. Besa C, Lewis S, Pandharipande PV, et al. Hepatocellular carcinoma detection: diagnostic performance of a simulated abbreviated MRI protocol combining diffusion-weighted and T1-weighted imaging at the delayed phase post gadoxetic acid. Abdom Radiol (NY). 2017 Jan;42(1):179-190. PMID: 27448609
  18. Wagner M, Corcuera-Solano I, Lo G, Esses S, Liao J, Besa C, Chen N, Abraham G, Fung M, Babb JS, Ehman RL, Taouli B. Technical Failure of MR Elastography Examinations of the Liver: Experience from a Large Single-Center Study. Radiology. 2017 Jan 3:160863. PMID: 28045604. Hectors SJ, Besa C, Wagner M, Jajamovich GH, Haines GK 3rd, Lewis S, Tewari A, Rastinehad A, Huang W, Taouli B. DCE-MRI of the prostate using shutter-speed vs. Tofts model for tumor characterization and assessment of aggressiveness. J Magn Reson Imaging. 2017 Jan 1. PMID: 28092414
  19. Gordic S, Corcuera-Solano I, Stueck A, Besa C, Argiriadi P, Guniganti P, King M, Kihira S, Babb J, Thung S, Taouli B. Evaluation of HCC response to locoregional therapy: Validation of MRI-based response criteria versus explant pathology. J Hepatol. 2017 Aug 18. PMID: 28823713
  20. Azour L, Besa C, Lewis S, Kamath A, Oliver ER, Taouli B. The gravid uterus: MR imaging and reporting of abnormal placentation. Abdom Radiol (NY). 2016 Dec;41(12):2411-2423.
  21. Besa C, Ward S, Cui Y, Jajamovich G, Kim M, Taouli B. Neuroendocrine liver metastases: Value of apparent diffusion coefficient and enhancement ratios for characterization of histopathologic grade. J Magn Reson Imaging. 2016 Dec;44(6):1432-1441. PMID: 27227756
  22. Huang W, Chen Y, Fedorov A, et al. The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge. Tomography : a journal for imaging research. 2016;2(1):56-66.
  23. Wagner M, Besa C, Bou Ayache J, et al. Magnetic Resonance Elastography of the Liver: Qualitative and Quantitative Comparison of Gradient Echo and Spin Echo Echoplanar Imaging Sequences. Investigative radiology. 2016;51(9):575-81.
  24. Lewis S, Vasudevan P, Chatterji M, Besa C et al. Comparison of gadoxetic acid to gadobenate dimeglumine for assessment of biliary anatomy of potential liver donors. Abdominal radiology. 2016;41(7):1300-9.
  25. Hectors SJ, Wagner M, Besa C, et al. Intravoxel Hectors SJ, Wagner M, Besa C, et al. Intravoxel incoherent motion diffusion-weighted imaging of hepatocellular carcinoma: Is there a correlation with flow and perfusion metrics obtained with dynamic contrast-enhanced MRI? J Magn Reson Imaging. 2016 Oct;44(4):856-64. PMID: 26919327
  26. Jajamovich GH, Huang W, Besa C, et al. DCE-MRI of hepatocellular carcinoma: perfusion quantification with Tofts model versus shutter-speed model–initial experience. 2016;29(1):49-58.
  27. Yasar TK, Wagner M, Bane O, Besa C, et al. Interplatform reproducibility of liver and spleen stiffness measured with MR elastography. Journal of magnetic resonance imaging : JMRI. 2016;43(5):1064-72.
  28. Bane O, Besa C, Wagner M, et al. Feasibility and reproducibility of BOLD and TOLD measurements in the liver with oxygen and carbogen gas challenge in healthy volunteers and patients with hepatocellular carcinoma. Journal of magnetic resonance imaging : JMRI. 2016;43(4):866-76.
  29. Cui Y, Dyvorne H, Besa C, Cooper N, Taouli B. IVIM Diffusion-weighted Imaging of the Liver at 3.0T: Comparison with 1.5T. European Journal of Radiology Open. 2015;2:123-8.
  30. Besa C, Bane O, Jajamovich G, Marchione J, Taouli B. 3D T1 relaxometry pre and post gadoxetic acid injection for the assessment of liver cirrhosis and liver function. Magnetic resonance imaging. 2015;33(9):1075-82.
  31. Mani V, Alie N, Ramachandran S, Robson PM, Besa C et al. A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis. Journal of visualized experiments : JoVE. 2015(100):e52761.
  32. Satkunasingham J, Besa C, Bane O, et al. Liver fat quantification: Comparison of dual-echo and triple-echo chemical shift MRI to MR spectroscopy. European journal of radiology. 2015;84(8):1452-8.
  33. Besa C, Kakite S, Cooper N, Facciuto M, Taouli B. Comparison of gadoxetic acid and gadopentetate dimeglumine-enhanced MRI for HCC detection: prospective crossover study at 3 T. Acta radiologica. 2015;4(2):2047981614561285.
  34. Dyvorne HA, Knight-Greenfield A, Besa C, et al. Quantification of hepatic blood flow using a high-resolution phase-contrast MRI sequence with compressed sensing acceleration. AJR American journal of roentgenology. 2015;204(3):510-8.
  35. Dyvorne H, Knight-Greenfield A, Jajamovich G, Besa C, et al. Abdominal 4D flow MR imaging in a breath hold: combination of spiral sampling and dynamic compressed sensing for highly accelerated acquisition. Radiology. 2015;275(1):245-54.
  36. Dyvorne HA, Jajamovich GH, Besa C, Cooper N, Taouli B. Simultaneous measurement of hepatic and splenic stiffness using MR elastography: preliminary experience. Abdominal imaging. 2015;40(4):803-9.
  37. Kakite S, Dyvorne H, Besa C, et al. Hepatocellular carcinoma: short-term reproducibility of apparent diffusion coefficient and intravoxel incoherent motion parameters at 3.0T. Journal of magnetic resonance imaging : JMRI. 2015;41(1):149-56.
  38. Caselli Morgado G, Besa C, Miguieles Cocco R, Bellolio Roth F, Molina Pezoa ME. [Tranverse colon volvulus]. Acta gastroenterologica Latinoamericana. 2013;43(4):301-3.
  39. Yaghmai V, Besa C, Kim E, Gatlin JL, Siddiqui NA, Taouli B. Imaging assessment of hepatocellular carcinoma response to locoregional and systemic therapy. AJR American journal of roentgenology. 2013;201(1):80-96.
  40. Carrasco G, Besa C, Lewis SC, Kadri HS, Hiotis S, Thung SN. Telangiectatic hyperplastic nodule associated with vascular malformation in a patient with chronic hepatitis B: radiologic and pathologic features. Seminars in liver disease. 2013;33(2):178-84
  41. Retamal J, Libuy J, Jimenez M, Delgado M, Besa C, et al. Preliminary study of ventilation with 4 ml/kg tidal volume in acute respiratory distress syndrome: feasibility and effects on cyclic recruitment – derecruitment and hyperinflation. Critical care. 2013;17(1):R16.

 

  1. Besa C, Cruz JP, Huete A, Cruz F. Portal biliopathy: a multitechnique imaging approach. Abdominal imaging. 2012;37(1):83-90.
  2. Aruta C, Besa C, et al. Double-balloon endoscopy and small bowel polyps resection in Peutz-Jeghers syndrome: report of 3 cases. Gastroenterol Latinoam 2011; Vol 22, N 4: 311-316
  3. Bruhn A, Bugedo D, Riquelme F, Varas J, Retamal J, Besa C, Cabrera C, Bugedo G. Tidal volume is a major determinant of cyclic recruitment-derecruitment in acute respiratory distress syndrome.Minerva Anestesiol. 2011 Apr;77(4):418-26
  4. Caselli G, Besa C, Pulgar D. Intestinal obstruction as manifestation of a multifocal colonic endometriosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2011;9(9):e90-1.
  5. Besa C y cols. Osteonecrosis como manifestación inicial de neoplasias sistémicas: Reporte de 3 casos y revision bliográfica. Rev Colomb Radiol 2010; 20(3): 2729-33

Proyectos:

Investigador Asociado Núcleo Milenio Imágenes Cardiovasculares – Cardio MR.

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