Dr. Francisco Barrera M.

Hígado graso, Carcinoma hepatocelular, Cirrosis, sarcopenia, ejercicio.

Cargo


Profesor Asociado

Contacto


fjbarrer@uc.cl

Área de Investigación Doctorado Ciencias Médicas:

Cáncer

Líneas de Investigación:

  • Hígado graso
  • Carcinoma hepatocelular
  • Cirrosis, sarcopenia, ejercicio

Proyectos vigentes:

  • FONDECYT Regular 1191183, Dissecting therapeutic role of Growth Hormone and Insulin-like Growth Factor 1 in chronic liver disease: balancing between hepatocyte protection and oncogenic potential (Abril 2019 – Marzo 2023).

Publicaciones relevantes:

  • Fernández-Mincone T, Contreras-Briceño F, Espinosa-Ramírez M, García-Valdés P, López-Fuenzalida A, Riquelme A, Arab JP, Cabrera D, Arrese M, Barrera F. Nonalcoholic fatty liver disease and sarcopenia: pathophysiological connections and therapeutic implications. Expert Rev Gastroenterol Hepatol. 2020 Dec;14(12):1141-1157. doi: 10.1080/17474124.2020.1810563. Epub 2020 Sep 11. PMID: 32811209.

  • Cabrera D, Cabello-Verrugio C, Solís N, San Martín D, Cofré C, Pizarro M, Arab JP, Abrigo J, Campos F, Irigoyen B, Carrasco-Avino G, Bezares K, Riquelme V, Riquelme A, Arrese M, Barrera F. Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease: Beneficial Hepatic and Systemic Effects of Hormone Supplementation. Int J Mol Sci. 2018 May 2;19(5):1339. doi: 10.3390/ijms19051339. PMID: 29724029; PMCID: PMC5983806.

  • Barrera F, Azócar L, Molina H, Schalper KA, Ocares M, Liberona J, Villarroel L, Pimentel F, Pérez-Ayuso RM, Nervi F, Groen AK, Miquel JF. Effect of cholecystectomy on bile acid synthesis and circulating levels of fibroblast growth factor 19. Ann Hepatol. 2015 Sep-Oct;14(5):710-21. PMID: 26256900.

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