Dr. Gabriel Rada G.

Medicina Interna

Profesor Asociado de la Facultad de Medicina y director del Centro Evidencia UC, de la Pontificia Universidad Católica de Chile. Es cofundador, presidente y director ejecutivo de la Fundación Epistemonikos, una organización sin fines de lucro cuya misión es acercar la información independiente, de alta calidad a todos quienes toman decisiones en salud, por medio del uso de tecnologías de la información.

Cargo

Profesor Asociado

Teléfono

(+56)2 22345905

Contacto

gabriel@rada.cl

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Pregrado:

Medicina. Pontificia Universidad Católica de Chile (Fecha egreso Diciembre 2001).

Postgrado:

Medicina Interna, Pontificia Universidad Católica de Chile (Fecha egreso Mayo 2005). Aprobado con Distinción.

Otros:

Diplomado en docencia, Centro de educación Médica. Pontificia Universidad Católica de Chile (Fecha egreso: Junio 2008).

Actividades docente-asistenciales:

  • Profesor asociado del Departamento de Medicina Interna de la Pontificia Universidad Católica de Chile. Categoría ordinaria. Contrato por 44 horas.
  • Director del Centro Evidencia UC (previamente Programa de Salud Basada en Evidencia) de la Pontificia Universidad Católica de Chile, desde 2013 hasta la fecha.
  • Fundador de Epistemonikos, presidente y director ejecutivo de Fundación Epistemonikos
  • Director de Cochrane Chile, desde 2017 hasta la fecha.
  • Editor del grupo EPOC de la Colaboración Cochrane (Effective Practice and Organization of Care Cochrane Review Group)

Proyectos de Investigación:

  • Cofounder and Chair. Epistemonikos project. http://foundation.epistemonikos.org/ (since 2012)
  • Transform project: Game Changers initiative 2014, The Cochrane Collaboration. 2015-2017
  • DECIDE project: European Union Seventh Framework Programme (FP7 – HEALTH.2010.3.1-1 – two stage) under grant agreement n° 258583. 2011-2015.
  • ‘Communicate to vaccinate (COMMVAC) 2: Implementing communication interventions to improve childhood vaccination uptake in LICs’. Norwegian Research Council. 2013-2016.
  • Deputy principal investigator. [Evidence-based Policy brief: Alternatives at School to decrease Child Obesity] Resumen de políticas: Alternativas de intervención en la escuela para disminuir la obesidad infantil. II concurso políticas públicas “propuestas para chile”: 2012
  • Deputy principal investigator. [Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death]. FONIS: National Fund for Research and Development in Health, Chile. Amiodarona comparado con otras intervenciones farmacológicas para la prevención de muerte súbita cardiaca. VII° Concurso FONIS, 2012.
  • Principal Investigator [Efficacy, Costs and Satisfaction of a model of Hospital-at-Home as early discharge from Hospital in Low and Moderate Risk Patients] FONIS: National Fund for Research and Development in Health, Chile. Eficacia, costos y satisfaccion usuaria de la hospitalizacion endomicilio como modelo de alta precoz desde el hospital, en pacientes de riesgo bajo y moderado. V° Concurso FONIS, 2008.
  • Deputy principal investigator [What is the Minimal Dose of Proton-Pump Inhibitors to Prevent Peptic Ulcer Rebleeding] FONIS: National Fund for Research and Development in Health, Chile. ¿Cuál es la mínima dosis útil de inhibidores de la bomba de protones para prevenir el resangrado por ulcera péptica? V° Concurso FONIS, 2008.
  • Researcher [Intensified Insulin Therapy versus Standard Care for Medical Inpatients] FONIS: National Fund for Research and Development in Health, Chile. Insulinoterapia intensificada versus terapia habitual en pacientes hospitalizados por patología médica. V° Concurso FONIS, 2008.
  • Principal Investigator. Strengthening Health Policy and Systems Research methodologies and promoting their sound teaching: Searching databases for systematic reviews in health policy and systems research.Alliance for Health Policy and Systems Research (World Health Organization). 2008-2009
  • Centre for systematic review of health policy and systems research in low and middle income countries. Alliance for Health Policy and Systems Research (World Health Organization). 2007-2009.

Áreas de Investigación:

  • Information technologies to improve access and assessment of research, with emphasis in Evidence-based Health Care and Evidence-informed Policy-making.
  • Design and conduction of systematic reviews in clinical and health systems issues.
  • Member of the Iberoamerican Cochrane Network since 2001, and co-director of the Southern South American branch of the Iberoamerican Cochrane network since 2009. Editor of Cochrane Effective Practice and Organisation of Care Review Group since 2013.
  • Member of GRADE working group

Publicaciones:

  1. Moberg J, Oxman AD, Rosenbaum S, Schünemann HJ, Guyatt G, Flottorp S, Glenton
    C, Lewin S, Morelli A, Rada G, Alonso-Coello P; GRADE Working Group. The GRADE
    Evidence to Decision (EtD) framework for health system and public health
    decisions. Health Res Policy Syst. 2018 May 29;16(1):45. doi:
    10.1186/s12961-018-0320-2.
  2. Irarrázaval S, Alegría Mejías AI, Bravo Soto G, Rada G. Diacerein and arthrosis treatment. Medwave. 2018 Apr 13;18(2):e7202. doi: 10.5867/medwave.2018.02.7202.
  3. Canales J, Rada G. Are probiotics effective in preventing urinary tract infection? Medwave. 2018 Apr 4;18(2):e7186. doi: 10.5867/medwave.2018.02.7185.
  4. Johansen M, Rada G, Rosenbaum S, Paulsen E, Motaze NV, Opiyo N, Wiysonge CS, Ding Y, Mukinda FK, Oxman AD. A comparative evaluation of PDQ-Evidence. Health Res Policy Syst. 2018 Mar 15;16(1):27. doi: 10.1186/s12961-018-0299-8.
  5. Rocco M, Rada G. Are cannabinoids effective for fibromyalgia? Medwave. 2018 Feb 14;18(1):e7154. doi: 10.5867/medwave.2018.01.7153.
  6. Contreras T, Bravo-Soto G, Rada G. Do cannabinoids constitute a therapeutic alternative for insomnia? Medwave. 2018 Feb 13;18(1):e7152. doi: 10.5867/medwave.2018.01.7151. Spanish, English. PubMed PMID: 294743
  7. Inzunza G, Rada G, Majerson A. Bipolar or monopolar transurethral resection for benign prostatic hyperplasia? Medwave. 2018 Jan 17;18(1):e7134. doi: 10.5867/medwave.2018.01.7134.
  8. Alarcón-Andrade G, Bravo-Soto G, Rada G. Are systemic corticosteroids useful for the management of acute pharyngitis? Medwave. 2017 Dec 26;17(9):e7111. doi: 10.5867/medwave.2017.09.7111.
  9. Núñez A, Núñez C, Corsi O, Rada G. Are cannabinoids effective for HIV wasting syndrome? Medwave. 2017 Dec 22;17(9):e7107. doi: 10.5867/medwave.2017.09.7107.
  10. Contreras T, Bravo-Soto GA, Rada G. Do cannabinoids constitute a therapeutic alternative for anorexia nervosa? Medwave. 2017 Dec 1;17(9):e7095. doi: 10.5867/medwave.2017.09.7095.
  11. Canales JP, Castro V, Rada G. Are vaginal estrogens effective for preventing urinary tract infection in postmenopausal women? Medwave. 2017 Nov 21;17(9):e7093. doi: 10.5867/medwave.2017.09.7093.
  12. Oku A, Oyo-Ita A, Glenton C, Fretheim A, Ames H, Muloliwa A, Kaufman J, Hill S, Cliff J, Cartier Y, Owoaje E, Bosch-Capblanch X, Rada G, Lewin S. Perceptions and experiences of childhood vaccination communication strategies among caregivers and health workers in Nigeria: A qualitative study. PLoS One. 2017 Nov 8;12(11):e0186733. doi: 10.1371/journal.pone.0186733.
  13. Ciapponi A, Lewin S, Herrera CA, Opiyo N, Pantoja T, Paulsen E, Rada G, Wiysonge CS, Bastías G, Dudley L, Flottorp S, Gagnon MP, Garcia Marti S, Glenton C, Okwundu CI, Peñaloza B, Suleman F, Oxman AD. Delivery arrangements for health systems in low-income countries: an overview of systematic reviews. Cochrane Database Syst Rev. 2017 Sep 13;9:CD011083. doi: 10.1002/14651858.CD011083.pub2.
  14. Pantoja T, Opiyo N, Lewin S, Paulsen E, Ciapponi A, Wiysonge CS, Herrera CA, Rada G, Peñaloza B, Dudley L, Gagnon MP, Garcia Marti S, Oxman AD. Implementation strategies for health systems in low-income countries: an overview of systematic reviews. Cochrane Database Syst Rev. 2017 Sep 12;9:CD011086. doi: 10.1002/14651858.CD011086.pub2.
  15. Herrera CA, Lewin S, Paulsen E, Ciapponi A, Opiyo N, Pantoja T, Rada G, Wiysonge CS, Bastías G, Garcia Marti S, Okwundu CI, Peñaloza B, Oxman AD. Governance arrangements for health systems in low-income countries: an overview of systematic reviews. Cochrane Database Syst Rev. 2017 Sep 12;9:CD011085. doi: 10.1002/14651858.CD011085.pub2.
  16. Wiysonge CS, Paulsen E, Lewin S, Ciapponi A, Herrera CA, Opiyo N, Pantoja T, Rada G, Oxman AD. Financial arrangements for health systems in low-income countries: an overview of systematic reviews. Cochrane Database Syst Rev. 2017 Sep 11;9:CD011084. doi: 10.1002/14651858.CD011084.pub2.
  17. Ballesteros M, Montero N, López-Pousa A, Urrútia G, Solà I, Rada G, Pardo-Hernandez H, Bonfill X. Evidence mapping based on systematic reviews of therapeutic interventions for gastrointestinal stromal tumors (GIST). BMC Med Res Methodol. 2017 Sep 7;17(1):135. doi: 10.1186/s12874-017-0402-9.
  18. Cifuentes I, Dagnino B, Rada G. Do textured breast implants decrease the rate of capsular contracture compared to smooth implants? Medwave. 2017 Aug 31;17(7):e7020. doi: 10.5867/medwave.2017.7020.
  19. Ames H, Njang DM, Glenton C, Fretheim A, Kaufman J, Hill S, Oku A, Cliff J, Cartier Y, Bosch-Capblanch X, Rada G, Muloliwa AM, Oyo-Ita A, Kum AP, Lewin S. Stakeholder perceptions of communication about vaccination in two regions of Cameroon: A qualitative case study. PLoS One. 2017 Aug 31;12(8):e0183721. doi: 10.1371/journal.pone.0183721.
  20. Kaufman J, Ryan R, Lewin S, Bosch-Capblanch X, Glenton C, Cliff J, Oyo-Ita A, Muloliwa AM, Oku A, Ames H, Rada G, Cartier Y, Hill S. Identification of preliminary core outcome domains for communication about childhood vaccination: An online Delphi survey. Vaccine. 2017 Aug 20. pii: S0264-410X(17)31094-0. doi: 10.1016/j.vaccine.2017.08.027.
  21. Alonso-Coello P, Schünemann HJ, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Rada G, Rosenbaum S, Morelli A, Guyatt GH, Oxman AD; el GRADE Working Group. [GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction]. Gac Sanit. 2017 Aug 17. pii: S0213-9111(17)30121-8. doi: 10.1016/j.gaceta.2017.02.010.
  22. Guinguis R, Ruiz MI, Rada G. Is cannabidiol an effective treatment for schizophrenia? Medwave. 2017 Aug 9;17(7):e7010. doi: 10.5867/medwave.2017.07.7010.
  23. Allende-Salazar RF, Rada G. Are cannabinoids an effective treatment for chronic non-cancer pain? Medwave. 2017 Jun 14;17(Suppl2):e6972. doi: 10.5867/medwave.2017.6972.
  24. Muloliwa AM, Cliff J, Oku A, Oyo-Ita A, Glenton C, Ames H, Kaufman J, Hill S, Cartier Y, Bosch-Capblanch X, Rada G, Lewin S. Using the COMMVAC taxonomy to map vaccination communication interventions in Mozambique. Glob Health Action. 2017;10(1):1321313. doi: 10.1080/16549716.2017.1321313.
  25. Pinos Y, Ruiz MI, Corsi Ó, Rada G. Is it worth adding loperamide to antibiotic treatment of traveler’s diarrhea? Medwave. 2017 May 23;17(Suppl 2):e6958. doi: 10.5867/medwave.2017.6958.
  26. Kaufman J, Ames H, Bosch-Capblanch X, Cartier Y, Cliff J, Glenton C, Lewin S, Muloliwa AM, Oku A, Oyo-Ita A, Rada G, Hill S. The comprehensive ‘Communicate to Vaccinate’ taxonomy of communication interventions for childhood vaccination in routine and campaign contexts. BMC Public Health. 2017 May 10;17(1):423. doi: 10.1186/s12889-017-4320-x.
  27. Rain C, Rada G. Are statins beneficial for chronic heart failure? First update. Version 2. Medwave. 2017 Apr 25 [revised 2017 Apr 28];17(Suppl2):e6853. doi: 10.5867/medwave.2017.6853.
  28. Bennett-Laso JT, Kramer-Urrutia T, Rada G. Should we administer oxygen during an acute coronary syndrome? Medwave. 2017 Mar 29;17(Suppl1):e6892. doi: 10.5867/medwave.2017.6892
  29. Meza R, Rada G, Varas P. Are steroids effective in toxic epidermal necrolysis and Stevens-Johnson syndrome? Medwave. 2017 Apr 5;17(Suppl2):e6894. doi: 10.5867/medwave.2017.6894.
  30. Meza R, Peña J, García K, Corsi O, Rada G. Are cannabinoids effective in multiple sclerosis? Medwave. 2017 Mar 10;17(Suppl1):e6865. doi: 10.5867/medwave.2017.6865.
  31. Kaufman J, Ryan R, Glenton C, Lewin S, Bosch-Capblanch X, Cartier Y, Cliff J, Oyo-Ita A, Ames H, Muloliwa AM, Oku A, Rada G, Hill S. Childhood vaccination communication outcomes unpacked and organised in a taxonomy to facilitate core outcome establishment. J Clin Epidemiol. 2017 Feb 23. pii: S0895-4356(16)30545-5. doi: 10.1016/j.jclinepi.2017.02.007.
  32. Oku A, Oyo-Ita A, Glenton C, Fretheim A, Eteng G, Ames H, Muloliwa A, Kaufman J, Hill S, Cliff J, Cartier Y, Bosch-Capblanch X, Rada G, Lewin S. Factors affecting the implementation of childhood vaccination communication strategies in Nigeria: a qualitative study. BMC Public Health. 2017 Feb 15;17(1):200. doi: 10.1186/s12889-017-4020-6.
  33. Oku A, Oyo-Ita A, Glenton C, Fretheim A, Ames H, Muloliwa A, Kaufman J, Hill S, Cliff J, Cartier Y, Bosch-Capblanch X, Rada G, Lewin S. Communication strategies to promote the uptake of childhood vaccination in Nigeria: a systematic map. Glob Health Action. 2016 Jan;9(1):30337. doi: 10.3402/gha.v9.30337.
  34.  Ruiz MI, Aceituno D, Rada G. Art therapy for schizophrenia? Medwave. 2017 Jan 19;17(Suppl1):e6845. doi: 10.5867/medwave.2017.6845.
  35. Peña J, Rada G. Are cannabinoids effective for epilepsy? Medwave. 2017 Jan 13;17(Suppl1):e6821. doi: 10.5867/medwave.2017.6821.
  36. Castro-Gutiérrez V, Rada G. Is fluid restriction needed in heart failure? Medwave. 2017 Jan 9;17(Suppl1):e6817. doi: 10.5867/medwave.2017.6817.
  37. Bravo-Soto GA, Llovet-Gutiérrez V, Rada G. Are perioperative statins beneficial for cardiac surgery? Medwave. 2017 Jan 16;17(Suppl1):e6834. doi: 10.5867/medwave.2017.6834.
  38. Pinos Y, Castro-Gutiérrez V, Rada G. Are probiotics effective to prevent traveler’s diarrhea? Medwave. 2016 Dec 23;16(Suppl5):e6807. doi: 10.5867/medwave.2016.6807.
  39. García K, Rada G. Do cannabinoids have a role to play in Tourette’s syndrome? Medwave. 2016 Dec 9;16(Suppl5):e6793. doi: 10.5867/medwave.2016.6793.
  40. Armstrong A, Rada G, Altermatt F. Is perioperative beta-blockade effective and safe in patients undergoing noncardiac surgery? Medwave. 2016 Dec 27;16(Suppl5):e6819. doi: 10.5867/medwave.2016.6819.
  41. Vergara M, Castro-Gutiérrez V, Rada G. Do branched chain amino acids improve hepatic encephalopathy in cirrhosis? Medwave. 2016 Dec 14;16(Suppl5):e6795. doi: 10.5867/medwave.2016.6795.
  42. Araneda D, Rada G. Are erythropoiesis-stimulating agents beneficial for anemia in chronic heart failure patients? Medwave. 2016 Nov 23;16(Suppl5):e6607. doi: 10.5867/medwave.2016.6607.
  43.  Castro-Gutiérrez V, Rada G. Should sodium intake be restricted in chronic heart failure? Medwave. 2016 Dec 5;16(Suppl5):e6696. doi: 10.5867/medwave.2016.6696.
  44. Alegría J, Rada G. Are beta-blockers effective in heart failure with preserved ejection fraction? Medwave. 2016 Nov 2;16(Suppl5):e6593. doi: 10.5867/medwave.2016.6593.
  45. Alegría J, Rada G. Are beta-blockers effective in heart failure with preserved ejection fraction? Medwave. 2016 Nov 2;16(Suppl5):e6593. doi: 10.5867/medwave.2016.6593.
  46. Triantafilo N, Castro-Gutiérrez V, Rada G. Cabergoline or bromocriptine for prolactinoma? Medwave. 2016 Sep 15;16(Suppl3):e6545. doi: 10.5867/medwave.2016.6545.
  47. Llovet V, Rada G. Does Helicobacter pylori eradication play a role in immune thrombocytopenia? Medwave. 2016 Sep 5;16 Suppl 3:e6528. doi: 10.5867/medwave.2016.6528. English, Spanish. PubMed PMID: 27603101.
  48. Damiani F, Rada G, Gana JC, Brockmann PE, Alberti G. Long-term effects of adenotonsillectomy in children with obstructive sleep apnoea: protocol for a systematic review. BMJ Open. 2016 Sep 2;6(9):e010030. doi: 10.1136/bmjopen-2015-010030.
  49. Castro-Gutiérrez V, Rada G. Is there a role for glutamine supplementation in the management of acute pancreatitis? Medwave. 2016 Aug 17;16 Suppl 3:e6512. doi: 10.5867/medwave.2016.6512.
  50. Gaitonde R, Oxman AD, Okebukola PO, Rada G. Interventions to reduce corruption in the health sector. Cochrane Database Syst Rev. 2016 Aug 16;(8):CD008856. doi: 10.1002/14651858.CD008856.pub2.
  51. Izcovich A, Popoff F, Rada G. Early mobilization versus bed rest for deep vein thrombosis. Medwave. 2016 Jun 28;16 Suppl 2:e6478. doi: 10.5867/medwave.2016.6478.
  52. Villalón A, Olmos R, Rada G. Are higher doses of proton pump inhibitors better in acute peptic bleeding? Medwave. 2016 Jun 24;16 Suppl 2:e6476. doi: 10.5867/medwave.2016.6476.
  53. Rada G, Arteaga M, Candia R. Is pentoxifylline effective in alcoholic hepatitis? –First update. Version 2. Medwave. 2016 Jun 14 [revised 2016 Jan 1];16 Suppl 2:e6469. doi: 10.5867/medwave.2016.6469.
  54. Alonso-Coello P, Schünemann HJ, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Rada G, Rosenbaum S, Morelli A, Guyatt GH, Oxman AD; GRADE Working Group. GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction. BMJ. 2016 Jun 28;353:i2016. doi: 10.1136/bmj.i2016.
  55. Koch E, Rada G. Is preemptive antifungal therapy a good alternative to empirical treatment in prolonged febrile neutropenia? Medwave. 2016 Jun 9;16(Suppl2):e6463. doi: 10.5867/medwave.2016.6463.
  56. Walbaum B, Valda ML, Rada G. Sodium restriction in patients with cirrhotic ascites: a protocol for a systematic review. Syst Rev. 2016 May 10;5(1):78. doi: 10.1186/s13643-016-0250-4.
  57. Ahumada V, Moraga F, Rada G. Laparoscopy or open surgery for the treatment of hydatid cyst? Medwave. 2016 Mar 22;16(Suppl 1):e6385. doi: 10.5867/medwave.2016.6385.
  58. López CS, Saka CH, Rada G, Valenzuela DD. Impact of fixed implant supported prostheses in edentulous patients: protocol for a systematic review. BMJ Open. 2016 Feb 23;6(2):e009288. doi: 10.1136/bmjopen-2015-009288.
  59. Oku A, Oyo-Ita A, Glenton C, Fretheim A, Ames H, Muloliwa A, Kaufman J, Hill S, Cliff J, Cartier Y, Bosch-Capblanch X, Rada G, Lewin S. Communication strategies to promote the uptake of childhood vaccination in Nigeria: a systematic map. Glob Health Action. 2016 Feb 12;9:30337. doi: 10.3402/gha.v9.30337.
  60. Pérez F, Rada G. Is antibiotic prophylaxis in nasal packing for anterior epistaxis needed? Medwave. 2016 Jan 7;16(Suppl 1):e6357. doi: 10.5867/medwave.2015.6357.
  61. Tortorolo F, Farren F, Rada G. Is melatonin useful for jet lag? Medwave. 2015 Dec 21;15(Suppl 3):e6343. doi: 10.5867/medwave.2015.6343.
  62. Pérez E, Rada G, Maul E. Selective laser trabeculoplasty compared with

medical treatment for the initial management of open angle glaucoma or ocular hypertension. Medwave. 2015 Dec 16;15(Suppl 3):e6337. doi: 10.5867/medwave.2015.6337.

  1. Flores S, Avilés C, Rada G. Is tranexamic acid effective for acute upper

gastrointestinal bleeding? Medwave. 2015 Dec 7;15(Suppl 3):e6330. doi:

10.5867/medwave.2015.6330.

  1. Ames H, Njang DM, Glenton C, Fretheim A, Kaufman J, Hill S, Oku A, Cliff J, Cartier Y, Bosch-Capblanch X, Rada G, Muloliwa A, Oyo-Ita A, Lewin S. Mapping how information about childhood vaccination is communicated in two regions of Cameroon: What is done and where are the gaps? BMC Public Health. 2015 Dec 21;15(1):1264. doi: 10.1186/s12889-015-2557-9.
  2. Claro JC, Candia R, Rada G, Baraona F, Larrondo F, Letelier LM. Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death. Cochrane Database Syst Rev. 2015 Dec 8;12:CD008093. doi: 10.1002/14651858.CD008093.pub2. Review. PubMed PMID: 26646017.
  3. Arenas A, Rada G. Are prophylactic antibiotics useful in chronic obstructive

pulmonary disease? Medwave. 2015 Nov 10;15(Suppl 3):e6309. doi: 10.5867/medwave.2015.6309.

  1. Kaufman J, Ryan R, Bosch-Capblanch X, Cartier Y, Cliff J, Glenton C, Lewin S, Rada G, Ames H, Muloliwa AM, Oku A, Oyo-Ita A, Hill S. Outcomes mapping study for childhood vaccination communication: too few concepts were measured in too many ways. J Clin Epidemiol. 2015 Oct 16. pii: S0895-4356(15)00467-9. doi: 10.1016/j.jclinepi.2015.10.003.
  2. Aravena C, Labarca G, Venegas C, Arenas A, Rada G. Correction: Pirfenidone for Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis. PLoS One. 2015 Oct 6;10(10):e0140288. doi: 10.1371/journal.pone.0140288. eCollection 2015. 
  3. Rada G. Telemedicine: are we advancing the science? Cochrane Database Syst Rev. 2015 Sep 8;9:ED000105. doi: 10.1002/14651858.ED000105.
  4. Rada G. Four states of mind of the evidence-based practitioner – On the receiving end of the first FRISBEE supplement. Medwave. 2015 Aug 27;15(7):e6237. doi: 10.5867/medwave.2015.07.6237.
  5. Walbaum B, Rada G. Is there benefit adding antivirals to corticosteroids for Bell’s palsy in adults? Medwave. 2015 Aug 21;15 Suppl 2:e6226. doi: 10.5867/medwave.2015.6226.
  6. Celis P, Rada G. High-dose inhaled corticosteroids or addition of theophylline in patients with poorly controlled asthma? Medwave. 2015 Aug 19;15 Suppl 2:e6224. doi: 10.5867/medwave.2015.6224.
  7. Rain C, Yáñez T, Rada G. Is rituximab effective for induction of remission in ANCA-associated vasculitis? Medwave. 2015 Aug 13;15 Suppl 2:e6209. doi: 10.5867/medwave.2015.6209.
  8. Rada G, Bachelet VC. Epistemonikos summaries in Medwave: reliable and user-friendly evidence that is here to stay. Medwave. 2015 Aug 26;15(7):e6232. doi: 10.5867/medwave.2015.6232
  9. Celis P, Rada G. Noradrenaline or terlipressin for hepatorenal syndrome? Medwave. 2015 Aug 27;15 Suppl 2:e6235. doi: 10.5867/medwave.2015.6235.
  10. Meneses C, Rada G. What are the effects of adding azathioprine to corticosteroids in polymyositis? Medwave. 2015 Jul 8;15 Suppl 1:e6179. doi: 10.5867/medwave.2015.6179.
  11. Rain C, Rada G. Is there any difference between angiotensin converting enzyme inhibitors and angiotensin receptor blockers for heart failure? Medwave. 2015 Jul 6;15 Suppl 1:e6177. doi: 10.5867/medwave.2015.06.6177.
  12. Bonfill X, Osorio D, Posso M, Solà I, Rada G, Torres A, García Dieguez M, Piña-Pozas M, Díaz-García L, Tristán M, Gandarilla O, Rincón-Valenzuela DA, Martí A, Hidalgo R, Simancas-Racines D, López L, Correa R, Rojas-De-Arias A, Loza C, Gianneo Ó, Pardo H; Iberoamerican Cochrane Network. Identification of biomedical  journals in Spain and Latin America. Health Info Libr J. 2015 Dec;32(4):276-86. doi: 10.1111/hir.12110.
  13. Rain C, Rada G. Is carvedilol better than other beta-blockers for heart failure? Medwave. 2015 Jun 26;15 Suppl 1:e6168. doi: 10.5867/medwave.2015.6168.
  14. Rada G, Viñuela J. Does chewing gum improve recovery after an abdominal surgery?–First update. Version 2. Medwave. 2015 Jun 18 [revised 2015 Jun 18];15  Suppl 1:e6162. doi: 10.5867/medwave.2015.6162.
  15. Rain C, Rada G. Is there a role for digitalis in chronic heart failure?–First update. Version 2. Medwave. 2015 Jun 5 [revised 2015 Jun 5];15 Suppl 1:e6148. doi: 10.5867/medwave.2015.6149.
  16. Rain C, Rada G. Are statins beneficial for chronic heart failure? Medwave. 2015 May 27;15(4):e6140. doi: 10.5867/medwave.2015.04.6140.
  17. Rada G, Peña J. Is antibiotic prophylaxis beneficial in acute pancreatitis?–First update. Medwave. 2015 Apr 23;15(3):e6125. doi: 10.5867/medwave.2015.03.6125.
  18. Izcovich A, Rada G. Should acetylcysteine be used to prevent contrast induced nephropathy? Medwave. 2015 Apr 15;15(3):e6122. doi: 10.5867/m edwave.2015.03.6122.
  19. Rain C, Rada G. Are angiotensin-converting enzyme inhibitors or angiotensin 2 receptor antagonists effective in heart failure with preserved ejection fraction? Medwave. 2015 Mar 19;15(2):e6101. doi: 10.5867/medwave.2015.02.6101.
  20. Lustig N, Rada G. Is iloprost effective in secondary Raynaud’s phenomenon? Medwave. 2015 Mar 9;15(2):e6082. doi: 10.5867/medwave.2015.02.6082.
  21. Rada G, Peña J. Is antibiotic prophylaxis beneficial in acute pancreatitis? –  First update. Medwave. 2015 Apr 23;15(3):e6125. Doi: 10.5867/medwave.2015.03.6125
  22. Rada G. La escalera evolutiva del revisor Cochrane. Revista CONAMED 2015;20(1):38-44.
  23. Herrera CA, Rada G, Kuhn-Barrientos L, Barrios X. Does ownership matter? An overview of systematic reviews of the performance of private for-profit, private not-for-profit and public healthcare providers. PLoS One. 2014 Dec 1;9(12):e93456. doi: 10.1371/journal.pone.0093456
  24. Rada G, Viñuela J. [Does chewing gum accelerate recovery after abdominal surgery?]. Medwave. 2014 Dec 23;14(11):e6058. doi: 10.5867/medwave.2014.11.6058.
  25. Véliz D, Rada G. [Does preoperative intravitreal bevacizumab reduce complications of vitrectomy for proliferative diabetic retinopathy?]. Medwave 2014 Dec 12;14(11):e6052. doi: 10.5867/medwave.2014.11.6052.
  26. Rada G. [Quick evidence reviews using Epistemonikos: a thorough, friendly and current approach to evidence in health]. Medwave. 2014 Jul 15;14(6):e5997. doi:10.5867/medwave.2014.06.5997.
  27. Rada G, Neumann I, Cerda J. A new way to find evidence quickly and efficiently. Medwave. 2014 Nov 27;14(10):e6044. doi: 10.5867/medwave.2014.10.6044
  28. Neumann I, Rada G. [Evidence-based decision-making: when it is worthwhile]. Medwave. 2014 Jun 11;14(5):e5966. doi: 10.5867/medwave.2014.05.5966.
  29. Rada G, Arteaga M. [Is pentoxifylline effective in alcoholic hepatitis?].Medwave. 2014 Jul 29;14(6):e6002. doi: 10.5867/medwave.2014.06.6002. Spanish.PubMed PMID: 25353639.
  30. Rada G, Peña J. [Are aldosterone antagonists effective in patients with mild to moderate heart failure?]. Medwave. 2014 Jul 15;14(6):e5999. doi: 10.5867/medwave.2014.06.5999. Spanish. PubMed PMID: 25353251.
  31. Navajas L, Rada G. [Is intravenous immunoglobulin effective in toxic epidermal necrolysis and Stevens-Johnson syndrome?]. Medwave. 2014 Oct 17;14(9):e6024. doi: 10.5867/medwave.2014.09.6024. Spanish. PubMed PMID: 25340656.
  32. Mac-Namara M, Rada G. [Is rituximab effective for induction of remission in lupus nephritis?]. Medwave. 2014 Aug 25;14(7):e6010. doi: 10.5867/medwave.2014.07.6010. Spanish. PubMed PMID: 25334007.
  33. Peña J, Garrido M, Rada G. [Is perioperative chemotherapy effective in patients with resectable gastric cancer?]. Medwave. 2014 Aug 18;14(7):e6008. doi: 10.5867/medwave.2014.07.6008. Spanish. PubMed PMID: 25333926.
  34. Rada G, Peña J. [Is antibiotic prophylaxis in acute pancreatitis beneficial?]. Medwave. 2014 Aug 6;14(7):e6004. doi: 10.5867/medwave.2014.07.6004. Spanish. PubMed PMID: 25333686.
  35. Elliott J, Sim I, Thomas J, Owens N, Dooley G, Riis J, Wallace B, Thomas J, Noel-Storr A, Rada G, Struthers C, Howe T, MacLehose H, Brandt L, Kunnamo I, Mavergames C. CochraneTech: technology and the future of systematic reviews.Cochrane Database Syst Rev. 2014 Sep 19;9:ED000091. PubMed PMID: 25313416.
  36. Rada G, Mac-Namara M. [Is ursodeoxycholic acid effective in primary biliary cirrhosis?]. Medwave. 2014 Sep 24;14(8):e6019. doi: 10.5867/medwave.2014.08.6019. Spanish. PubMed PMID: 25291185.
  37. Rada G. Thimerosal in vaccines – white, black, or quite the opposite?. Medwave. 2014 Mar 31;14(2):e5929. doi: 10.5867/medwave.2014.02.5929. English, Spanish. PubMed PMID: 25198357.
  38. Neumann I, Pantoja T, Peñaloza B, Cifuentes L, Rada G. [The GRADE system: a change in the way of assessing the quality of evidence and the strength of recommendations].. Rev Med Chile   2014;142(5): 630-635.
  39. Bravo C, Rondon Clavo CM, Oliva P, Rada G, Rivera-Cornejo M, Torres-Robles R. Percutaneous coronary intervention versus coronary artery bypass grafting for adults with diabetes and multivessel coronary disease (Protocol). Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD011012. DOI: 10.1002/14651858.CD011012
  40. Bachelet VC, Rada G. Why the Helsinki Declaration now encourages trial registration, and publication and dissemination of the results of research. Medwave 2013;13(10):e5846 doi: 10.5867/medwave.2013.10.5846
  41. Rada G, Pérez D, Capurro D. Epistemonikos: a free, relational, collaborative, multilingual database of health evidence. Stud Health Technol Inform. 2013;192:486-90.
  42. Cerda J, Vera C, Rada G. [Odds ratio: theoretical and practical issues]. Rev

Med Chil. 2013 Oct;141(10):1329-35

  1. Rada G. The requirement to disclose individual patient data in clinical studies will bring down the wall behind which the pharmaceutical industry hides the truth: the Kerkoporta is ajar. Medwave 2013;13(5):e5735 doi: 10.5867/medwave.2013.05.5735
  2. Neumann I, Letelier LM, Rada G, Claro JC, Martin J, Howden CW, Yuan Y, Leontiadis GI. Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD007999. DOI: 10.1002/14651858.CD007999.pub2.
  3. Rada G, Schünemann HJ, Labedi N, El-Hachem P, Kairouz VF, Akl EA. Systematic evaluation of the methodology of randomized controlled trials of anticoagulation in patients with cancer. BMC Cancer. 2013 Feb 14;13:76.
  4. Claro JC, Lustig N, Soto M, Rada G. [First step: the clinical question]. Rev Med Chil. 2012 Aug;140(8):1067-72.
  5. Rada G. Epistemonikos: Base de datos de evidencia en múltiples idiomas.Boletín ANM-Venezuela.  Julio 2012. Volumen 4, Nº 43, Sección IV.
  6. Carrasco-Labra A, Brignardello-Petersen R, Yanine N, Araya I, Rada G, Chadwick RG. Professionally-applied chemically-induced whitening of teeth in adults (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010379.
  7. Neumann I, Rada G, Claro JC, Carrasco-Labra A, Thorlund K, Akl EA, et al. Oral Direct Factor Xa Inhibitors Versus Low-Molecular-Weight Heparin to Prevent Venous Thromboembolism in Patients Undergoing Total Hip or Knee Replacement: A Systematic Review and Meta-analysis. Ann Intern Med. 2012 May 15;156(10):710-9
  8. Rojas P, Rada G. Antibióticos en otitis media aguda, ¿son necesarios?, ¿existe algún subgrupo que se beneficia? . Rev Med Chil. 2012;140(5):pendiente.
  9. Neumann I, Rada G, Claro JC, Carrasco-Labra A, Thorlund K, Akl EA, et al. Inhibidores directos del Factor Xa para la prevención del tromboembolismo en pacientes sometidos a reemplazo total de cadera o de rodilla. Protocolo de una revisión sistemática. Ars Medica. 2012;1(1):4.
  10. Candia R, Rada G. Detención Precoz de Estudios Clínicos Randomizados: ¿Beneficio para los pacientes o para el investigador?: Sobrestimación de resultados, Reglas de Detención y Comités de Monitorización de Datos. Ars Medica. 2012;1(1):6.
  11. Dagnino J, Cerda LJ, Rada G. Ars Medica, la nueva. Ars Medica. 2012;1(1):1.
  12. Rada G. ¿Son efectivas las intervenciones para reducir el consumo de sodio en la dieta? Ars Medica. 2012. 1(1):
  13. Rada G, Letelier L. Intervenciones para reducir el consumo de sal en la dieta: la importancia de transmitir la evidencia en forma clara a quienes más la necesitan Medwave. 2012;12(2).
  14. Rada G. Epistemonikos: la forma más rápida y fiable de encontrar evidencia. Evid Pediatr. 2012;8:28.
  15. Peñaloza B, Pantoja T, Bastías G, Herrera C, Rada G. Interventions to reduce emigration of health care professionals from low- and middle-income countries. Cochrane Database of Systematic Reviews 2011, Issue 9. Art. No.: CD007673. DOI: 10.1002/14651858.CD007673.pub2.
  16. Rada G, Neumann I, Roa M, Rojas L. Antioxidants for acute pancreatitis (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 3. Art. No.: CD009049. DOI: 10.1002/14651858.CD009049.
  17. Neumann I, Grassi B, Bdair F, Rada G. Antiproteases for acute pancreatitis (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 11. Art. No.: CD009426. DOI: 10.1002/14651858.CD009426.
  18. Cabezón M, Rada G. Análisis crítico de un artículo: colonografía por tomografía computada tuvo buen rendimiento para la pesquisa de cáncer colorrectal en pacientes de alto riesgo. Rev Med Chil. 2011;139(5):675-680. 
  19. Rada G, Capurro D, Pantoja T, Corbalán J, Moreno G, Letelier LM, Vera C. Non-hormonal interventions for hot flushes in women with a history of breast cancer. Cochrane Database of Systematic Reviews 2010, Issue 9. Art. No.: CD004923. DOI: 10.1002/14651858.CD004923.pub2.
  20. Gajardo P, Cabezón, Rada G. Descripción de las publicaciones de la Revista Otorrinolaringología y Cirugía de Cabeza y Cuello durante los años 2003 a 2008. Revista Otorrinolaringología y Cirugía de Cabeza y Cuello. 2010;70:25-30
  21. Peñaloza B, Rada G, Pantoja T, Bastías G, Herrera C. Interventions for controlling emigration of health professionals from low and middle-income countries (Protocol). Cochrane Database of Systematic Reviews 2009, Issue 1. Art. No.: CD007673. DOI: 10.1002/14651858.CD007673.
  22. Rada G, Roa M. Qué son y cómo se interpretan los outcomes compuestos. Rev med Chil. 2009;137(11):1523-1526. doi: 10.4067/S0034-98872009001100019.
  23. Jiménez de la Jara J, Albala C, Bambs C, Cruz Mena E, Espinoza M, Margozzini P, Rada G, Marín PP. Medicina Interna y Salud Pública: Claves para una relación virtuosa. Rev Med Chil. 2009;137(8):1095-8.
  24. Rada G, Letelier LM. ¿Podemos mantenernos actualizados en medicina en el siglo XXI? Rev Med Chil. 2009;137:701-8
  25. Rada G. ACP Journal Club. Immediate and delayed acupuncture reduced frequency and pain intensity of primary migraine or tension-type headaches. Ann Intern Med. 2009 Jan 20;150(2):JC1-14.
  26. Roa M, Rada G. Análisis crítico de un artículo: La profilaxis primaria de peritonitis bacteriana espontánea  disminuye la aparición de síndrome hepatorrenal y mejora la sobrevida en pacientes cirróticos avanzados. Rev Med Chil 2008;136:1353-7
  27. Salech F, Mery V, Larrondo F, Rada G. Estudios que evalúan un test diagnóstico: interpretando sus resultados. Rev Med Chile, sep. 2008;136(9):1208-1208.
  28. Lewin S, Lavis JN, Oxman AD, Bastías G, Chopra M, Ciapponi A, Flottorp S, Martí SG, Pantoja T, Rada G, Souza N, Treweek S, Wiysonge CS, Haines A. Supporting the delivery of cost-effective interventions in primary health-care systems in low-income and middle-income countries: an overview of systematic reviews. Lancet. 2008 Sep 13;372(9642):928-39.
  29. Walley J, Lawn JE, Tinker A, de Francisco A, Chopra M, Rudan I, Bhutta ZA, Black RE; Lancet Alma-Ata Working Group: Epping-Jordan J, Ekman B, Flottorp SA, Haines A, Lavis J, Liljestrand J, Kidd M, Mant D, Patel V, Pantoja T, Rada G, Rohde J, Rifkin S, Souza NM, Treweek S, Wiysonge C. Primary health care: making Alma-Ata a reality. Lancet. 2008 Sep 13;372(9642):1001-7
  30. Letelier LM, Capurro D, Rada G. Our 6 years experience towards evidence-based clinical practice (EBCP): Evidence-Based Medicine Working Group. Evidence Based Health Care Newsletter. 2008;28:12-3
  31. Rada G, Letelier LM. Evidence Provision for Policy Makers in Low and Middle Income Countries (LMIC): A Chilean Experience. Evidence Based Health Care Newsletter. 2007;27:16-7
  32. Capurro D, Rada G. El proceso diagnóstico. Rev Med Chil 2007;135:530-534
  33. Abarza J, Rada G. Análisis crítico de un artículo: ¿Es seguro no tratar a pacientes con sospecha de tromboembolismo pulmonar y tomografía axial computarizada negativa? Rev Méd Chil 2007;135:535-539
  34. Candia R, Letelier LM, Rada G. Estudios randomizados interrumpidos precozmente por beneficio ¿muy buenos o muy malos? Rev Med Chil 2006;134(11):1470-5.
  35. Candia R, Rada G. Análisis crítico de un artículo: Levofloxacino profiláctico en pacientes neutropénicos. Rev Med Chil 2006;134(11):1476-9.
  36. Rada G, Andrade M. ¿Debo aplicar los resultados de este estudio a mi paciente? Rev Med Chil 2006;134(1):115-119
  37. Eymin G, Andresen M, Godoy J, Rada G. Síndrome neuroléptico maligno y poliserositis en paciente usuaria de clozapina: una asociación infrecuente. Rev Med Chil 2005;133(10):1225-1229
  38. Manriquez M J, Valdivia C G, Rada G G, Letelier S LM. Critical assessment of randomized controlled trials published in biomedical Chilean journals. Rev Med Chil 2005;133(4):439-46.          
  39. Letelier LM, Manríquez J, Rada G. Systematic reviews and metaanalysis: are the best evidence? Rev Med Chil 2005;133(2):246-249.
  40. Rada GA, Capurro D, Pantoja T, Corbalán J, Moreno G, Pacheco C, Letelier LM. Non hormonal interventions for hot flushes in women with a history of breast cancer. (Protocol) The Cochrane Database of Systematic Reviews 2004, Issue 3. Art. No.: CD004923. DOI: 10.1002/14651858.CD004923.
  41. Rada G, Andrade M, Leyton V et al. Search strategies in evidence-based medicine. Rev Med Chil 2004;132(2):253-259
  42. Rada G, Montero J. Análisis crítico de un artículo: El estudio ALLHAT: Diuréticos tipo tiazidas serían el fármaco de elección para iniciar tratamiento en hipertensión arterial. Rev Med Chil 2004;132(4):516-519
  43. Soto M, Rada G. Questions formulation in Evidence-Based Medicine. Rev Med Chil 2003;131(10):1202-3
  44. Vera C, Rada G. Terapia hormonal de reemplazo… primum non nocere: Principal Results From the Women’s Health Initiative Randomized Controlled Trial. Rev Med Chile 2003;131(8):951-953.
  45. Mardones F, Bastías G, Farías M, Dinamarca R, Olavaria F, Rada G, Rojas A, Rojas P. Composición corporal de neonatos con alteraciones en el crecimiento fetal. Rev Chil Pediatr 1999. 70(4);300-305.

Libros:

  • Co-author [Methodological Handbook for the Development of Clinical Practice Guidelines with GRADE methodology. Ministry of Health, Chile] Manual Metodológico para el Desarrollo de Guías de Práctica Clínica con Metodología GRADE. MINSAL, 2014
  • Letelier LM, Capurro D, Cerda J, Cifuentes Águila L, Claro JC, Rada G, Rivera Mercado S, Montori VM. Examples of Likelihood Ratios.” Users’ Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed Guyatt G, Rennie D, Meade MO, …
  • Co-author. Chapter 17.2: Letelier LM, Rada G, Capurro D, Rivera S, Montori V. Examples of Likelihood Ratio. En: User’s Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice textbook, edited by Gordon Guyatt and Drummond Rennie. 2ª Edición, 2008.
Facultad de Medicina UC
IMG_4735

Pontificia Universidad Católica de Chile 2019

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