Hematología-Oncología
Epigenética del cáncer gástrico
Cargo
Profesor Asociado
Contacto
corvalan@med.puc.cl
Áreas de Investigación Doctorado Ciencias Médicas:
Líneas de Investigación:
Publicaciones relevantes:
Torres K, Landeros N, Wichmann IA, Polakovicova I, Aguayo F, Corvalan AH. EBV miR-BARTs and human lncRNAs: Shifting the balance in competing endogenous RNA networks in EBV-associated gastric cancer. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166049. doi: 10.1016/j.bbadis.2020.166049. Epub 2021 Jan 2. PMID: 33401001.
Landeros N, Santoro PM, Carrasco-Avino G, Corvalan AH. Competing Endogenous RNA Networks in the Epithelial to Mesenchymal Transition in Diffuse-Type of Gastric Cancer. Cancers (Basel). 2020 Sep 24;12(10):2741. doi: 10.3390/cancers12102741. PMID: 32987716; PMCID: PMC7598708.
Alarcón MA, Olivares W, Córdova-Delgado M, Muñoz-Medel M, de Mayo T, Carrasco-Aviño G, Wichmann I, Landeros N, Amigo J, Norero E, Villarroel-Espíndola F, Riquelme A, Garrido M, Owen GI, Corvalán AH. The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer. Int J Mol Sci. 2020 Dec 12;21(24):9472. doi: 10.3390/ijms21249472. PMID: 33322837; PMCID: PMC7763358.
Proyectos vigentes:
FONDECYT Regular 1191928, The upregulation of long-noncoding RNA, a novel opportunity to address the complexities of the pathogenesis of gastric cancer. Investigador responsable: Alejandro Corvalán (Abril 2019 – Marzo 2023).
Proyecto FONDAP 15130011: MAUCO, Advanced Center for Chronic Diseases (ACCDiS). Investigador responsable: Alejandro Corvalán (2019 –2024).
Links de interés: