Departamento de Psiquiatría
Diagonal Paraguay 362, 5º Piso
Telefono: (56)(2) 3543028
Fax:  6651951
Jessica Reyes Salinas


Francisco Aboitiz Domínguez
Aboitiz Domínguez


Profesor titular

Marcoleta 391, 2 piso
(56-2) 2354 3808

Formación Pregrado :

1975 - 1983: Biología,  Universidad de Chile

Formación Postgrado :

1985 - 1991: Doctor of Philosophy in Neurosciece, Universidad de California.

1991 - 1992: Postdoctorado en Neurociencias, Universidad de California.

Líneas de Interés:
Neurociencia cognitiva.
Neurobiología comparada.

Actividades Docentes Asistenciales :

2003  - a la fecha : Profesor Colaborador. Curso Neurociencia, Licenciatura en Biología. , P. Universidad Católica 

2003  - a la fecha : Profesor Colaborador. Curso Bases Neurobiológicas de la Psiquiatría. Carrera de Medicina, 5º año. , P. Universidad Católica

2004  - a la fecha : Profesor Colaborador. Curso Neurofisiología. Carrera de Medicina PUC 2º año. , P. Universidad Católica

2004  - a la fecha : Introducción a la Neurociencia Cognitiva. Segundo semestre, Doctorado en Cs. Médicas. Director del curso. , P. Universidad Católica

2005 : Participación en el Diplomado en Trastornos de la Alimentación. Centro de Extensión.

2006 Director Diplomado "Bases Biológicas y Evolutivas de la Psiquiatria"

Otras Publicaciones :

- 2004 : Díaz-Veliz G, Mora S, Gomez P, Dossi MT, Montiel J, Arriagada C, Aboitiz F, Segura-Aguilar J. Behavioral effects of manganese injected in the rat substantia nigra are potentiated by dicumarol, a DT-diaphorase inhibitor. Pharmacology, Biochemistry and Behavior, 77:245-251.

- 2004 : Bosman C, García R, Aboitiz F. FOXP2 and the language working memory system. Trends in Cognitive Sciences, 8:251-252.

- 2004 : Aboitiz F., Schröter C. Prelinguistic evolution and motherese: a hypothesis on theneural substrates. Commentary . Behavioral and Brain Sciences, 27: 503-504.

- 2004 : Carrasco, X., Castillo, S., Aravena, T., Rothhammer, P. Aboitiz, F. Williams syndrome: Pediatric, neurological and cognitive development. Pediatric Neurology. 32: 166-172.

- 2004 : García R, Montiel JF, Villalón AU, Gatica MA, Aboitiz F. AChE-rich Magnopyramidal Neurons Have a Left-Right Size Asymmetry in Broca's Area. Brain Research, 1026:313-316.

- 2004 : Olivares R, Godoy G, Adaro L, Aboitiz F. Densidad neuronal en la corteza visual primaria en dos especies de roedores silvestres. International Journal of Morphology, 22:279-284.

- 2004 : Bosman C, Brunetti E, Aboitiz F. Schizophrenia is a disease of general connectivity more than of a specifically "social brain" network. Commentary. Behavioral and Brain Sciences, 27:856.

- 2005 : Bosman C, López V, Aboitiz F. Sharpening Occam's razor: is there necessity of a hand-signing stage prior to vocal communication? Commentary. Behavioral and Brain Sciences, 28:128-129.

- 2005 : Vargas A, Aboitiz F. How ancient is the adult swimming capacity in the lineage leading to euchordates?. Evolution and Development, 7:171-174.

- 2005 : Inestrosa NC , Reyes AE, Chacón MA, Villalón A, Montiel J, Merabachvili G, Aldunate R, Bozinovic F, Aboitiz F. Human-Like Rodent Amyloid-b-Peptide Determines Alzheimer Pathology in Aged Wild-type Octodon degu. Neurobiology of Aging. 26, 1023-1028.

- 2005 : Aboitiz F, Schröter C. Effective callosal connectivity is also a ratio. Commentary. Current Anthropology, 46:262-263.

- 2005 : Rojas D, Carmona-Fontaine C, López-Calderón J, Aboitiz F. Do discreteness and rivalry coexist in illusory motion reversals? Vision Research, 46:1155-1157.

- 2005 : Aboitiz F, García,R Brunetti E, Bosman C. Imitation and memory in language origins. Neural Networks, 18:1357

- 2005 : Aboitiz F, García R, Montiel J. Ancestry of the mammalian preplate and its derivatives: Evolutionary relicts or embryonic adaptations? Reviews in the Neurosciences, 16:359-376.

- 2005 : Dagnino, A., Terreros G., Carmona-Fontaine C., Zepeda R., Orellana JA., Diaz-Veli G,. Mora S. and Aboitiz F. Chronic stress impairs acoustic conditioning more than visual conditioning in rats: Morphological anda behavioural evidence. Neuroscience. 135: 1067-1074

- 2006 : Lopez V., Lopez J., Ortega R., Kreiter J., Carrasco X., Rothhammer P., Rothhammer F., Rosas R., Aboitiz, F. Attention-deficit hyperactivity disorder involves differential cortical processing in a visual spatial attention paradigm. Clinical Neurophysiology, en prensa. 

- 2006 : Carrasco X., Rothhammer P., Moraga M., Henríquez H., Chakraborty R., Aboitiz F. Rothhammer F. Genotipyc interaction between DRD4 and DAT1 loci is a high risk factor for attention-deficit/hyperactivity disorder in chilean families. American Journal of Medical Genetics Part B, 141B: 51-54, 2006.

- 2006 : Aboitiz F, Montiel J. Origin and evolution of the vertebrate telencephalon, with special reference to the mammalian neocortex. Advances in Anatomy, Embryology and Cell Biology, in press

- 2006 : Aboitiz F, García R, Bosman C, Brunetti E. Cortical memory mechanisms and language origins. Brain and Language, 98:40-56.

- 2006 : Dagnino-Subiabre A, Orellana JA, Carmona-Fontaine C, Montiel J, Díaz-Velíz G, Serón-Ferré M, Wyneken U, Concha ML, Aboitiz F.Chronic Stress Decreases the Expression of Sympathetic Markers in the Pineal Gland and Increases Plasma Melatonin Concentration in Rats . Journal of Neurochemistry, 97: 1279-1287.

- 2006 : Dagnino-Subiabre A, Díaz-Véliz G, Mora S, Aboitiz F. Chronic Stress Induces Up-Regulation of Brain-derived-neurotrophic-factor (BDNF) mRNA and Integrin α5 expression in the rat pineal gland. Molecular Brain Research, 1086: 27-34.

- 2006:  Aboitiz F, García R, Bosman C, Brunetti E. Cortical memory mechanisms and language origins. Brain and Language, 98:40-56.

- 2006 : López V, López J, Ortega R, Kreither J,  Carrasco X, Rothhammer P, Rothhammer F, Rosas R, Aboitiz F. Attention-Deficit Hyperactivity Disorder involves differential cortical processing in a visual spatial attention paradigm. Clinical Neurophysiology, 117:2540-2548. 

-2007: Aboitiz F, Montiel J.Origin and evolution of the vertebrate telencephalon, with special reference to the mammalian neocortex. Advances in Anatomy, Embryology and Cell Biology, 193:1-111.  

- 2007: Aboitiz F, López-Calderón J, López V. The mesencephalon as a source of preattentive consciousness. Commentary. Behavioral and Brain Sciences, 30: 81-82.

-2007: García R, Aboitiz F. Rescuing cortical mechanisms in the evolution of language. Comentary. Current Anthropology, 48:54.

- 2007: Ampuero E,  Dagnino-Subiabre A, Sandoval R, Zepeda-Carreño R; Sandoval S, Viedma A, Orrego F, Aboitiz F, Wyneken U. Status epilepticus induces region-specific changes in dendritic spines, dendritic length and TrkB protein content of rat brain cortex. Brain Research, 1150:225-238.

-2007: Aboitiz F, Montiel J. Co-option of signaling mechanisms from embryonic induction to telencephalic patterning. Reviews in the Neurosciences, 18:311-342.

-2007: Hamamé C, Cosmelli D, Aboitiz F. What is so informative about information? Commentary. Behavioral and Brain Sciences, 30:371-372.

-2008: LópezV, Pavez F, López-Calderón J, Ortega R, Sáez N, Carrasco X, Rothhammer P, Aboitiz F. Electrophysiological evidences of inhibition deficit in Attention-Deficit / Hyperactivity Disorder during the attentional blink. The Open Behavioral Science Journal, Bentham (new open-access Journal). 2:33-40.

-2008: Ortega R, López V, Aboitiz F. Voluntary modulations of attention in a semantic auditory-visual matching Task: an ERP study. Biological Research, 41:453-460. 

-2008: Henríquez H, Henríquez M, Carrasco X, Rothhammer P, Llop E, Aboitiz F, Rothhammer F. Combinación de genotipos DRD4 y DAT1 constituye importante factor de riesgo en miembros de familias de Santiago de Chile con déficit atencional. Revista Médica de Chile 136:719-724.

-2009: Aboitiz F, García R. Merging of phonological and gestural circuits in early language evolution. Reviews in the Neurosciences, 20:71-84..

-2009: Dagnino-Subiabre A, Muñoz-Llancao P, Terreros G, Wyneken U, Díaz-Véliz G, Porter B, Kilgard M, Atzori, M, Aboitiz F. Chronic Stress Induces Dendritic Atrophy in the Rat Medial Geniculate Nucleus: Effects on Auditory Conditioning. Behavioral Brain Research, 203:88-96. 

-2009: Gaspar PA, Bustamante ML, Silva H, Aboitiz F.Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications. Journal of Neurochemistry, 111:891-900.

-2010: BoseM, Muñoz-LlancaoP, RoychowdhuryS, NicholsJA, Jakkamsetti V, PorterB, ByrapureddyR, SalgadoH, Kilgar MP, Francisco Aboitiz  F, Dagnino-SubiabreA, Atzori M. Effect of the environment on the dendritic morphology of the rat auditory cortex. Synapse, 64:97-110. 

-2010: Henríquez M, Zamorano F, Rothhammer F, Aboitiz F. Modelos neurocognitivos para tdah y sus implicancias en el reconocimiento de eventuales endofenotipos. Neurocognitive models for adhd and their consequences on the searching of endophenotypes. Revista de Neurología, 50:109-116.

-2010: Bosman C, Zamorano F, Aboitiz F. Functional differences of low and high frequency oscillatory dynamics during illusory border perception. Brain Research, 1319:92-102.

-2010: Aboitiz F, Aboitiz S, García R. The phonological loop: a key innovation in human evolution. Current Anthropology, 51(S1):S55-S65. 

-2010: Ampuero E, RubioFJ, FalconR, SandovalM, Diaz-VelizG, GonzalezRE, ToledoJ, EarleN, Dagnino-SubiabreA, AboitizF, OrregoF, WynekenU. Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex. Neuroscience, 69(1):98-108.

-2010: Aboitiz F. A developmental approach to homology and brain evolution. Revista Chilena de Historia Natural, 83: 469-477.

-2011: Lagos LP, Silva C, Rothhammer P, Carrasco X, Llop E, Aboitiz F, Rothhammer F. Riesgo de trastorno por déficit atencional e hiperactividad en niños Aymara y de Rapa Nui: asociación con polimorfismos del sistema dopaminérgico. Revista Médica de  Chile, 139:600-605.

-2011: Cosmelli D, López V, Lachaux JP, López-Calderón J, RenaultB, Martinerie J, Aboitiz F. Shifting visual attention away from fixation is specifically associated with alpha band activity over ipsilateral parietal regions. Psychophysiology, 48(3):312-322.

-2011: Aboitiz F.Genetic and developmental homology in amniote brains. Toward conciliating radical views of brain evolution. Brain Research Bulletin, 84, 125-136.

-2011: Gaspar PA, Ruiz S, Zamorano F,  Altayó M, Pérez C, Bosman CA, Aboitiz F. (2011) P300 amplitude is insensitive to working memory load in schizophrenia. BMC Psychiatry, 11:29.

-2011 : Hamamé CM, Cosmelli D, Henríquez R, Aboitiz F. Neural Mechanisms of Human Perceptual Learning: Electrophysiological Evidence for a Two-Stage Process. PLoS One, 6(4):e19221.

 -2011: Gaspar  PA, Bosman CA, Ruiz S Zamorano F, Pérez C, Aboitiz F. Parametric increases of working memory load unveil a decreased alpha oscillatory activity in schizophrenia. Schizophrenia Research, 131:268-269.

 -2012: Aboitiz F, Montiel J. From tetrapods to primates: conserved developmental mechanisms in diverging ecological adaptations. Progress in Brain Research, 195: 3-24.

-2012: Aboitiz F. Gestures, vocalizations and memory in language origins. Frontiers in Evolutionary Neuroscience, 4:2. doi: 10.3389/fnevo.2012.00002.

-2012: OlivaresR, MorganC, PérezH, HernándezA, AboitizF,Soto-MoyanoR, GilJ, OrtizA, FloresO, GimenoM, LabordaJ. Anatomy of corpus callosum in rats malnourished prenatally. Biological Research, 44: 83-88.

-2012: CarrascoX, Daiber F, Rothhammer P, Huerta D, Andrade C, Opazo P, Lagos LP, RothhammerF, Aboitiz F. Attention deficit hyperactivity disorder in aymara children: a first clinical approach. Revista Médica de Chile, 140(11).

-2012: Rothhammer P, Lagos LP, Espinosa-Parrilla Y, Aboitiz F, RothhammerF. DRD4 dopamine receptor alleles in Chilean students of different ethnic origin and its relation with the risk for attention deficit/hyperactivity disorder. Revista Médica de Chile, 140: 1276-1281.

-2012: Henríquez-Henríquez M, Villarroel L, Henríquez H, Zamorano F, Rothhammer F, Aboitiz F. (2012)Intra-task variability as a correlate for DRD4 and SLC6A3 variants: a pilot study in Attention Deficit and Hyperactivity Disorder. Journal of Attention Disorders, EPub.

-2013: Billeke P, Zamorano F, Cosmelli D, Aboitiz F. Oscillatory brain activity correlates with risk perception and predicts social decisions. Cerebral Cortex, 23: 2872-2883.

-2013: Ortega R, López V, Carrasco X, Anllo-Vento L,  Aboitiz F.  Exogenous orienting of visual-spatial attention in ADHD children. Brain Research, 1493: 68-79.

-2013: Billeke P, Aboitiz F. Social cognition in schizophrenia:  from social stimuli processing to social engagement. Frontiers in Psychiatry, 4:4 doi: 10.3389/fpsyt.2013.00004. 

-2013: Amoruso L, Gelormini C, Aboitiz F, Alvarez-González M, Manes F, Cardona JF, Ibáñez A. (2013). N400 ERPs for actions: building meaning in context. Frontiers in Human Neuroscience, 7(57). doi: 10.3389/fnhum.2013.00057.

-2013: Brunetti E, Maldonado PE, Aboitiz F. Phase synchronization of delta and theta oscillations increase during the detection of relevant lexical information. Frontiers in Language Sciences, doi: 10.3389/fpsyg.2013.00308.

-2013: Aboitiz F. How did vocal behavior “take over” the gestural communication system? Language and Cognition, 5: 167-176.

-2013: Aboitiz F, Zamorano F. Neural Progenitors, patterning and ecology in neocortical origins. Frontiers in Neuroanatomy, 7:38. doi: 10.3389/fnana.2013.00038.

-2014: Zamorano F, Billeke P, Hurtado JM, López V, Carrasco X, Ossandón T, Aboitiz F. Temporal Constraints of Behavioral Inhibition: Relevance of Inter-stimulus Interval in a Go-Nogo Task. PloS One, 9(1): e87232.  doi:10.1371/journal.pone.0087232. 

-2014: Billeke P, Zamorano F, López T, Rodríguez C, Cosmelli D, Aboitiz F. Someone has to give in: theta oscillations correlate with adaptive behavior in social bargaining. Social, Cognitive and Affective Neuroscience, EPub. 

-2014: Aboitiz F, Ossandón T, Zamorano F, Palma B, Carrasco X.  Irrelevant stimulus processing in ADHD: catecholamine dynamics and attentional networks. Frontiers in Developmental Psychology, 5:183, doi: 10.3389/fpsyg.2014.00183.. 

-2014: Negrón I, Neira D, Espinosa N, Fuentealba P, Aboitiz F. Prenatal stress produces persistence of remote memory and disrupts functional connectivity in the hippocampal-prefrontal cortex axis. Cerebral Cortex, EPub.

-2014: García R, Zamorano F, Aboitiz F. from imitation to meaning: circuit plasticity and the acquisition of a primitive semantics. Frontiers in Human Neuroscience, 8:605 doi: 10.3389/fnhum.2014.00605..

-2014: Billeke P, Zamorano F, Chávez M, Cosmelli D, Aboitiz F. Functional cortical network in alpha band correlates with social bargaining. PloS One, 9:e109829. doi: 10.1371/journal.pone.0109829. 

-2014: García RR, Zamorano F, Aboitiz F. From imitation to meaning: circuit plasticity and the acquisition of a conventionalized semantics. Frontiers in Human Neuroscience, 8:605. 

-2015: Henríquez-Henríquez MP, Billeke P, Henríquez H, Zamorano FJ, Rothhammer F, Aboitiz F. Intra-individual response variability assessed by ex-gaussian analysismay be a new endophenotype for Attention Deficit/Hyperactivity Disorder. Frontiers in Psychiatry Ja12;5:197. doi: 10.3389/fpsyt.2014.00197.

Innocenti GM, Caminiti R, Aboitiz F. (2014) Comments on the paper by Horowitz et al. (2014). Brain Struct Funct. 2015 Jan 13 [Epub]

Palacios-García I, Lara-Vásquez A, Montiel JF, Díaz-Véliz GF, Sepúlveda H, Utreras E, Montecino M, González-Billault C, Aboitiz F. (2015) Prenatal Stress Down-regulates Reelin Expression by Methylation of its Promoter and Induces Adult Behavioral Impairments in Rats. PloS One, DOI:10.1371/journal.pone.0117680.

Billeke P, Armijo A, Castillo D, López T, Zamorano F, Cosmelli D, Aboitiz F. (2015). Paradoxical expectation: Oscillatory brain activity reveals social interaction impairment in schizophrenia . Biological Psychiatry, in press. 



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